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2013
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Wozniak MA and Itzhaki RF. (2013). Intravenous immunoglobulin reduces beta amyloid and abnormal tau formation caused by herpes simplex virus type 1. journal of neuroimmunology, eScholarID:187912
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2012
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Itzhaki RF and Wozniak MA. (2012). Could antivirals be used to treat Alzheimer's disease? Future Microbiology, 7(3), 307-309. eScholarID:187913
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2011
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Wozniak MA, Frost AL, Preston CM, Itzhaki RF. (2011). Antivirals reduce the formation of key Alzheimer's disease molecules in cell cultures acutely infected with herpes simplex virus type 1. PLoS One, 6(10), e25152. eScholarID:133508
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Ill-Raga G, Palomer E, Wozniak MA, Ramos-Fernández E, Bosch-Morató M, Tajes M, Guix FX, Galán JJ, Clarimón J, Antúnez C, Real LM, Boada M, Itzhaki RF, Fandos C, Muñoz FJ (2011). Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression. PLoS One, 6, eScholarID:130841
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2010
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M A Wozniak, R F Itzhaki. (2010). Antiviral agents in Alzheimer's disease: hope for the future? Therapeutic Advances in Neurological Disorders, 3(3), 141-152. eScholarID:82955 | DOI:10.1177/1756285610370069
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2009
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Wozniak, M., Frost, A. & Itzhaki, R (2009). Alzheimer's disease-specific tau phosphorylation is induced by herpes simplex virus type 1. J Alzheimers Dis, 16(2), 341-50. eScholarID:24561 | PMID:19221424 | DOI:10.3233/JAD-2009-0963
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Wozniak, M., Mee, A. & Itzhaki, R (2009). Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaques. J Pathol, 217(1), 131-8. eScholarID:24562 | PMID:18973185 | DOI:10.1002/path.2449
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Wozniak, M., Maude, R., Innes, J., Hawkey, P. & Itzhaki, R (2009). Apolipoprotein E-varepsilon2 confers risk of pulmonary tuberculosis in women from the Indian subcontinent - A preliminary study. J Infect, eScholarID:82954 | DOI:10.1016/j.jinf.2009.07.003
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2008
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Jayasuriya, A., Itzhaki, R., Wozniak, M., Patel, R., Smit, E., Noone, R., Gilleran, G., Taylor, S. & White, D (2008). Apolipoprotein E-epsilon 4 and recurrent genital herpes in individuals co-infected with herpes simplex virus type 2 and HIV. Sex Transm Infect, 84(7), 516-7. eScholarID:24563 | PMID:18708484 | DOI:10.1136/sti.2008.032367
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Itzhaki, R. & Wozniak, M (2008). Herpes simplex virus type 1 in Alzheimer's disease: the enemy within. J Alzheimers Dis, 13(4), 393-405. eScholarID:24566 | PMID:18487848
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Itzhaki, R. & Wozniak, M (2008). Alzheimer's disease-like changes in herpes simplex virus type 1 infected cells: the case for antiviral therapy. Rejuvenation Res, 11(2), 319-20. eScholarID:24567 | PMID:18328007 | DOI:10.1089/rej.2008.0673
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Itzhaki, R., Cosby, S. & Wozniak, M (2008). Herpes simplex virus type 1 and Alzheimer's disease: the autophagy connection. J Neurovirol, 14(1), 1-4. eScholarID:24568 | PMID:18300070 | DOI:10.1080/13550280701802543
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Itzhaki, R. & Wozniak, M (2008). Susceptibility to herpes simplex labialis conferred by the gene encoding apolipoprotein E. J Infect Dis, 198(4), 624-5; author reply 625-6. eScholarID:82953 | DOI:10.1086/590213
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2007
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Wozniak MA, Itzhaki RF, Shipley SJ, Dobson CB. (2007). Herpes simplex virus infection causes cellular beta-amyloid accumulation and secretase upregulation. Neuroscience Letters, 429, 95-100. eScholarID:1c7042 | PMID:17980964 | DOI:10.1016/j.neulet.2007.09.077
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Wozniak MA, Shipley SJ, Dobson CB, Parker SP, Scott FT, Leedham-Green M, Breuer J, Itzhaki RF. (2007). Does apolipoprotein E determine outcome of infection by varicella zoster virus and by Epstein Barr virus? European journal of human genetics : EJHG, 15(6), 672-8. eScholarID:1c6850 | PMID:17356546 | DOI:10.1038/sj.ejhg.5201812
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Itzhaki RF, Wozniak MA. (2007). Viral infection and cognitive decline. Journal of the American Geriatric Society, 51(1), 131. eScholarID:1c7051
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Itzhaki, R. & Wozniak, M (2007). Viral infection and cognitive decline. J Am Geriatr Soc, 55(1), eScholarID:82952 | DOI:10.1111/j.1532-5415.2006.01001.x
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2006
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Itzhaki RF, Wozniak MA. (2006). Herpes simplex virus type 1, apolipoprotein E, and cholesterol: a dangerous liaison in Alzheimer's disease and other disorders. Progress in lipid research, 45(1), 73-90. eScholarID:1c5836 | PMID:16406033 | DOI:10.1016/j.plipres.2005.11.003
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2005
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Shipley SJ, Parkin ET, Itzhaki RF, Dobson CB. (2005). Herpes simplex virus interferes with amyloid precursor protein processing. BMC Microbiology, 5(1), 48. eScholarID:1c3842 | PMID:16109164 | DOI:10.1186/1471-2180-5-48
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Wozniak MA, Shipley SJ, Combrinck M, Wilcock GK, Itzhaki RF. (2005). Productive herpes simplex virus in brain of elderly normal subjects and Alzheimer"s disease patients. Journal of medical virology, 75(2), 300-6. eScholarID:1c3843 | PMID:15602731 | DOI:10.1002/jmv.20271
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2004
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Itzhaki RF, Wozniak MA. (2004). Alzheimer"s disease, the neuroimmune axis, and viral infection. Journal of neuroimmunology, 156(1-2), 1-2. eScholarID:1c3844 | PMID:15526402 | DOI:10.1016/j.jneuroim.2004.07.006
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Itzhaki R. (2004). Herpes simplex virus type 1, apolipoprotein E and Alzheimer" disease. Herpes : the journal of the IHMF, 11 Suppl 2, 77A-82A. eScholarID:1c3845 | PMID:15319093
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Itzhaki RF, Dobson CB, Shipley SJ, Wozniak MA. (2004). The role of viruses and of APOE in dementia. Annals of the New York Academy of Sciences, 1019, 15-8. eScholarID:1c3846 | PMID:15246985 | DOI:10.1196/annals.1297.003
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Itzhaki RF, Wozniak MA, Appelt DM, Balin BJ. (2004). Infiltration of the brain by pathogens causes Alzheimer"s disease. Neurobiology of aging, 25(5), 619-27. eScholarID:1c3847 | PMID:15172740 | DOI:10.1016/j.neurobiolaging.2003.12.021
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Itzhaki RF, Dobson CB, Wozniak MA. (2004). Commentary on "Fast anterograde transport of herpes simplex virus: role for the amyloid precursor protein of Alzheimer"s disease" by Prasanna Satpute-Krishnan et al. Aging Cell Vol. 2, Issue 6, 305-318 (2003). Aging cell, 3(2), 79-80. eScholarID:1c3848 | PMID:15038823 | DOI:10.1111/j.1474-9728.2004.00088.x
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Wozniak MA, Riley EM, Itzhaki RF. (2004). Apolipoprotein E polymorphisms and risk of malaria. Journal of medical genetics, 41(3), 145-6. eScholarID:1c3849 | PMID:14985370 | DOI:10.1136/jmg.2003.014613
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Itzhaki RF, Dobson CB, Wozniak MA. (2004). Herpes simplex virus type 1 and Alzheimer"s disease. Annals of neurology, 55(2), 299-300; author reply 300-1. eScholarID:1c3850 | PMID:14755740 | DOI:10.1002/ana.10852
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Itzhaki RF, Wozniak MA, Dobson CB. (2004). Inflammatory consequences: benevolent, or virulent? Neurobiology of aging, 23(5), 681-2; discussion 683-4. eScholarID:1c3855 | PMID:12392772 | DOI:10.1016/S0197-4580(02)00033-7
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Itzhaki, R., Dobson, C. & Wozniak, M (2004). Commentary on 'Fast anterograde transport of herpes simplex virus: role for the amyloid precursor protein of Alzheimer's disease' by Prasanna Satpute-Krishnan et al. Aging Cell Vol. 2, Issue 6, 305-318 (2003). Aging Cell, 3(2), 79-80. eScholarID:82950 | DOI:10.1111/j.1474-9728.2004.00088.x
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Itzhaki, R., Dobson, C. & Wozniak, M (2004). Herpes simplex virus type 1 and Alzheimer's disease. Ann Neurol, 55(2), 299-300; author reply 300-1. eScholarID:82951 | DOI:10.1002/ana.10852
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2003
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Itzhaki, R., Irving, W. & Wozniak, M (2003). Apolipoprotein E and hepatitis C virus. Hepatology, 38(4), eScholarID:82949
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Itzhaki RF, Irving WL, Wozniak MA. (2003). Apolipoprotein E and hepatitis C virus. Hepatology (Baltimore, Md.), 38(4), 1060. eScholarID:1c3851 | PMID:14512896
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Wozniak MA, Cookson A, Wilcock GK, Itzhaki RF. (2003). Absence of Chlamydia pneumoniae in brain of vascular dementia patients. Neurobiology of aging, 24(6), 761-5. eScholarID:1c3852 | PMID:12927758 | DOI:10.1016/S0197-4580(02)00236-1
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Dobson CB, Wozniak MA, Itzhaki RF. (2003). Do infectious agents play a role in dementia? Trends in microbiology, 11(7), 312-7. eScholarID:1c3853 | PMID:12875814 | DOI:10.1016/S0966-842X(03)00146-X
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Wozniak MA, Faragher EB, Todd JA, Koram KA, Riley EM, Itzhaki RF. (2003). Does apolipoprotein E polymorphism influence susceptibility to malaria? Journal of medical genetics, 40(5), 348-51. eScholarID:1c3854 | PMID:12746397 | DOI:10.1136/jmg.40.5.348
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2002
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Grant WB, Campbell A, Itzhaki RF, Savory J. (2002). The significance of environmental factors in the etiology of Alzheimer"s disease. Journal of Alzheimer's disease : JAD, 4(3), 179-89. eScholarID:1c3856 | PMID:12226537
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Wozniak MA, Itzhaki RF, Faragher EB, James MW, Ryder SD, Irving WL. (2002). Apolipoprotein E-epsilon 4 protects against severe liver disease caused by hepatitis C virus. Hepatology (Baltimore, Md.), 36(2), 456-63. eScholarID:1c3857 | PMID:12143056 | DOI:10.1053/jhep.2002.34745
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Itzhaki RF, Dobson CB. (2002). Alzheimer"s disease and herpes. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 167(1), 13. eScholarID:1c3858 | PMID:12137067
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Lin WR, Wozniak MA, Cooper RJ, Wilcock GK, Itzhaki RF. (2002). Herpesviruses in brain and Alzheimer"s disease. The Journal of pathology, 197(3), 395-402. eScholarID:1c3859 | PMID:12115887 | DOI:10.1002/path.1127
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Lin WR, Wozniak MA, Wilcock GK, Itzhaki RF. (2002). Cytomegalovirus is present in a very high proportion of brains from vascular dementia patients. Neurobiology of disease, 9(1), 82-7. eScholarID:1c3860 | PMID:11848687 | DOI:10.1006/nbdi.2001.0465
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2001
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Lin WR, Jennings R, Smith TL, Wozniak MA, Itzhaki RF. (2001). Vaccination prevents latent HSV1 infection of mouse brain. Neurobiology of aging, 22(5), 699-703. eScholarID:1c3861 | PMID:11705626 | DOI:10.1016/S0197-4580(01)00239-1
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Itzhaki RF, Dobson CB, Lin WR, Wozniak MA. (2001). Association of HSV1 and apolipoprotein E-varepsilon4 in Alzheimer"s disease. Journal of neurovirology, 7(6), 570-1. eScholarID:1c3862 | PMID:11704890 | DOI:10.1080/135502801753248169
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Lin WR, Wozniak MA, Esiri MM, Klenerman P, Itzhaki RF. (2001). Herpes simplex encephalitis: involvement of apolipoprotein E genotype. Journal of neurology, neurosurgery, and psychiatry, 70(1), 117-9. eScholarID:1c3863 | PMID:11118260 | DOI:10.1136/jnnp.70.1.117
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Itzhaki, R., Dobson, C., Lin, W. & Wozniak, M (2001). Association of HSV1 and apolipoprotein E-varepsilon4 in Alzheimer's disease. J Neurovirol, 7(6), 570-1. eScholarID:82948 | DOI:10.1080/135502801753248169
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1999
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Dobson CB, Itzhaki RF. (1999). Herpes simplex virus type 1 and Alzheimer"s disease. Neurobiology of aging, 20(4), 457-65. eScholarID:1c3864 | PMID:10604441
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1998
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Dobson CB, Graham J, Itzhaki RF. (1998). Mechanisms of uptake of gallium by human neuroblastoma cells and effects of gallium and aluminum on cell growth, lysosomal protease, and choline acetyl transferase activity. Experimental neurology, 153(2), 342-50. eScholarID:1c3867 | PMID:9784293
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Dobson CB, Day JP, King SJ, Itzhaki RF. (1998). Location of aluminium and gallium in human neuroblastoma cells treated with metal-chelating agent complexes. Toxicology and applied pharmacology, 152(1), 145-52. eScholarID:1c3868 | PMID:9772210
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Itzhaki, R., Wozniak, M., Dobson, C. & Lin, W (1998). ApoE-viral interactions. Nat Med, 4(12), eScholarID:82947
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