Molecular and Cell Biology Systems:
Wellcome Trust Four Year PhD
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The Dynamics of Cellular Pathways
Understanding complex systems remains a major challenge for biologists. Large protein complexes are crucial for most major cellular events, from cell division, cell motility and adhesion, to cell death and differentiation. These proteins are then incorporated into pathways. Many basic cellular functions depend on these pathways, including protein secretion and endocytosis, cell recognition and cell signalling, as well as control of gene expression. Importantly, it is increasingly recognised that regulatory dynamics play a key role in controlling the activity of cellular pathways and that study of these pathways needs a more integrated holistic approach to research. The study of the dynamics of biological pathway function is the subject of our Wellcome Trust four year PhD programme, in particular relating to the following important processes:
- organelle biogenesis and membrane trafficking
- extracellular matrix, cell adhesion and the cytoskeleton
- cell division, apoptosis and development
- cell signalling and gene expression
The Programme offers an integrated approach to graduate education in a dynamic, well-funded environment. The first year consists of three short research projects and Programme-specific taught elements. Students are then well-equipped to choose their PhD research topic for the remaining three years. A generous stipend plus research and travel funds are provided by the Wellcome Trust.
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