Publications
The recent publications listed below give an idea of the type of work that is carried out by researchers within the Cell Organisation and Dynamics group.
Alcock F, Swanton E. (2009) Mammalian OS-9 is upregulated in response to endoplasmic reticulum stress and facilitates ubiquitination of misfolded glycoproteins. Journal of Molecular Biology, 385(4), 1032-42. Full text DOI:10.1016/j.jmb.2008.11.045 | PubMed entry PMID:19084021
Chiu, C.F., Ghanekar, Y., Frost L., Diao, A., Morrison, D., McKenzie, E., and Lowe, M. (2008). ZFPL1, a novel ring finger protein required for cis-Golgi integrity and efficient ER to Golgi transport. EMBO J. 27, 934-947.
Doyotte A, Mironov A, McKenzie E, Woodman P. (2008). The Bro1-related protein HD-PTP/PTPN23 is required for endosomal cargo sorting and multivesicular body morphogenesis. Proceedings of the National Academy of Sciences of the United States of America, 105(17), 6308-13. Full text DOI:10.1073/pnas.0707601105 | PubMed entry PMID:18434552
Driskell, O.J., Mironov, M., Allan, V. J. and Woodman, P.G. (2007) Dynein is required for receptor sorting and the morphogenesis of early endosomes. Nature Cell Biol. 9:113-120.
Etchells, J. & Turner, S (2010). The PXY-CLE41 receptor ligand pair defines a multifunctional pathway that controls the rate and orientation of vascular cell division. Development (Cambridge, England), 137(5), 767-74. Full text DOI:10.1242/dev.044941 | PubMed entry PMID:20147378
Fisher, K., and Turner, S. (2007). PXY, a receptor-like kinase essential for maintaining polarity during plant vascular-tissue development. Current Biology 17, 1061-1066.
Hale SJ, Lovell SC, de Keyzer J and Stirling CJ. (2010). Interactions between Kar2p and its nucleotide exchange factors Sil1p and Lhs1p are mechanistically distinct. J Biol Chem, 285(28), 21600-21606.
Lam C, Vergnolle MA, Thorpe L, Woodman PG, Allan VJ. (2010). Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning. Journal of Cell Science, 123(2), 202-212.
Morgan, B., Ang, S., Yan, G. & Lu, H (2009). Zinc can play chaperone-like and inhibitor roles during import of mitochondrial small Tim proteins. The Journal of Biological Chemistry, 284 (11), 6818-25. Full text DOI:10.1074/jbc.M808691200 | PubMed entry PMID:19117943
Pawel Leznicki, Anne Clancy, Blanche Schwappach and Stephen High. (2010). Bat3 promotes the membrane integration of tail-anchored proteins. Journal of Cell Science, 123, 2170-2178. Full text doi:10.1242/jcs.066738
Pool MR (2009) A trans-membrane segment inside the ribosome exit tunnel
triggers RAMP4 recruitment to the Sec61 translocase. J. Cell Biol. 185,
889-902.
Roboti, P., Swanton, E. & High, S. (2009). Differences in endoplasmic reticulum quality control determine the cellular response to disease-associated mutants of proteolipid protein. Journal of Cell Science, 122, 3942-3953.
Schuldiner M, Metz J, Schmid V, Denic, V, Rakwalska M, Schmitt HD, Schwappach B, Weissman JS (2008) The GET Complex Mediates Insertion of Tail-Anchored Proteins into the ER Membrane. Cell 134: 634-645.
Wilson, C.M., Roebuck, Q.P. & High, S. (2008). Ribophorin I regulates substrate delivery to the oligosaccharyl-transferase core. Proc. Natl. Acad. Sci. USA 105: 9534-9539.
Zhao, J., Connorton, J., Guo, Y., Li, X., Shigaki, T., Hirschi, K. & Pittman, J (2009). Functional studies of split Arabidopsis Ca2+/H+ exchangers. Journal of Biological Chemistry, 284(49), 34075-34083. Full text DOI:10.1074/jbc.M109.070235 | PubMed entry PMID:19819871