Neurosciences

Overview

As neuroscientists we study the brain and wider nervous system from its individual neuronal and glial component parts up to its activity as an integrated whole. We use this information to explain normal behaviours, to determine the origins and mechanisms of dysfunction and degeneration, and to devise new treatments.

The Neuroscience Research group has strong links with the Faculty of Medicine and Human Sciences, local hospitals and other research centres. These links are facilitated by the Neuroscience Research Institute, that brings together neuroscientists in Manchester and across the North West.

Research group leader: Dr Stuart Allan

Principal investigators

Members

Stuart Allan - Inflammation in acute and chronic neurodegenerative disease
Richard Baines - Acquisition of electrical properties in embryonic neurons
Enrico Bracci - Electrophysiology and biophysics of the basal ganglia
David Brough - Triggers and mechanisms of inflammation following brain injury
Maria Canal - Development and early programming of the circadian clock; effects on physiology and behaviour
Fred Cody - Control of human voluntary movement and its abnormalities in neurological disorders
Alan Crossman - Elucidation of the neural mechanisms that underlie movement disorders (such as Parkinson's disease and dyskinesias) and the development of new treatments
Natalie Gardiner - Extracellular matrix and the sensory nervous system. Pathogenesis of diabetic neuropathy
John Gigg - Mammalian hippocampal formation
Nicholas Glossop - Molecular control of clock cell development and maintenance
Ken Grieve - Neurophysiology of the visual brain
Ruth Itzhaki - Cell and molecular biology of Alzheimer's disease and neurovirology
Catherine Lawrence - How changes in energy balance influence central nervous system disease
Andrew Loudon - Molecular mechanisms controlling seasonal and circadian timing
Rob Lucas - Retinal function and circadian clocks
Simon Luckman - Central regulation of appetite and body energy levels
Catherine McCrohan - Comparative neurophysiology and behaviour of invertebrates
Qing-Jun Meng - Clocks, ageing and diseases
Jaleel Miyan - The role of cerebrospinal fluid in normal and abnormal brain development and the role of nerve fibres in host defence and immunity
Marcelo Montemurro - Dynamics and information processing in neuronal populations
Rasmus Petersen - Somatosensation, neural coding and neural computation
Hugh Piggins - Neuropeptides and behaviour
Emmanuel Pinteaux - Mechanisms of extracellular matrix remodelling in inflammatory responses to central nervous system disorders
Nancy Rothwell - Actions of inflammatory molecules in the brain
David Sattelle - Exploring mechanisms and routes to therapy for brain and neuromuscular disorders using C. elegans. Ligand-gated Ion channels as targets for human and animal health drugs.
Ingo Schiessl - Intrinsic functional brain imaging and investigation of the hemodynamic response function
Neil Todd - The human vestibular system
Jon Turner - Neurophysiology of sensorimotor and mnemonic systems, and the impact of disease states
Alexej Verkhratsky - Regulation of neuronal endoplasmic reticulum calcium stores by intraluminal calcium
Anne White - Neuroendocrine regulatory networks in obesity and diabetes

Affiliates

Matthew Cobb - Behaviour genetics, olfaction and chemical communication
Curtis Dobson - Novel host / pathogen interactions in the CNS: a basis for developing new anti-infective drugs?
Emma Gowen - Cognitive neuroscience
Owen Jones - Targeting of ion channels in the central nervous system
Niall McLoughlin - Brain imaging
Andreas Prokop - Molecular mechanisms underlying axonal growth and synapse formation