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Faculty of Life Sciences

Physiology

What is Physiology?

Physiology is the study of function in living systems. This can be in plants and animals but in Manchester we concentrate mainly on the function of humans/mammals. Physiologists work at the level of whole organisms, tissues, cells and now molecules, and we use a wide range of methods in our experiments. Research examines function in healthy tissues and diseased tissues. Our final year units reflect these interests, e.g. Clinical Endocrinology, Channels and Transporters in Health and Disease, the Cardiovascular System in Health and Disease, and Human Reproductive Biology. Teaching in the first two years of the course provides the necessary “bridge” between A-level Biology and these units. We also place an emphasis on laboratory skills which are taught in four stand-alone practical units.

Image of an insulin-secreting cell isolated from the rat pancreas.

Image of an insulin-secreting cell isolated from the rat pancreas.

Data graph.

Changes in insulin-secreting cell volume when the extracellular glucose concentration is increased from 4 mM to 20 mM.

Electrophysiological recording from the choroid plexus.

Electrophysiological recording from the choroid plexus. Inset: Activity of a single potassium channel in the choroid plexus cell membrane.

Data graph.

Group data from a second year practical showing the relationship between subject height and lung volume (vital capacity).

Data graph.

Tiny electrical currents carried by Na+ and Ca2+ channels in heart muscle cells. This recording was made by a final year student.